Merging highly recommends you defer updates in Windows 10, as major Windows updates can make your system unusable.
This allows such updates to be further tested and approved by Microsoft, and Merging.
Updates can be configured on Pro, Educational or Enterprise editions of Windows, not on home versions!
You may also rather Pause the updates for 30 days, follow this page for detailed instructions.

Pyramix 11.0.6 / Ovation 7.0.6 / VCube 7.0.6 / AMR 7.0.6 required for Windows 10 1709.
Pyramix 11.1.4 / Ovation 7.1.4 / VCube 7.1.4 / AMR 11.1.4 required for Windows 10 1803.
Pyramix 11.1.6 / Ovation 7.1.6 / VCube 7.1.6 / AMR 11.1.6 required for Windows 10 1809.
Pyramix 12.0.5 / Ovation 8.0.5 / VCube 8.0.5 / AMR 12.0.5 required for Windows 10 1903 and 1909.
Pyramix 25th / Ovation 9.0.3 / VCube 9.0.3 /AMR 13.0.3 compatible with Windows 10 November 2019 Update 1909
Pyramix 25th Hotfix 3 / Ovation 9.0.6 / VCube 9.0.6 /AMR 13.0.6 (or above) compatible with Windows 10 2004
Pyramix 25th Hotfix 3 / Ovation 9.0.6 / VCube 9.0.6 /AMR 13.0.6 (or above) compatible with Windows 10 20H2
Pyramix 25th Hotfix 3 / Ovation 9.0.6 / VCube 9.0.6 /AMR 13.0.6 (or above) compatible with Windows 10 21H1
Pyramix 25th Hotfix 3 / Ovation 9.0.6 / VCube 9.0.6 /AMR 13.0.6 (or above) compatible with Windows 10 21H2
Pyramix 25th Hotfix 3 / Ovation 9.0.6 / VCube 9.0.6 /AMR 13.0.6 (or above) compatible with Windows 10 22H2

Configure updates using Group Policy Editor

Windows Anniversary (1607), Creator (1703), Fall Creator (1709), Spring Creator (1803) October 2018 Update (1809) May 2019 Update (1903) November 2019 Update (1909) May 2020 (2004) Fall 2020 (20H2) May 2021 (21H1), November 2021 (21H2)

In Windows Search field, type GPEDIT.MSC
Right click on the gpedit.msc and select Run as Administrator

On Windows Anniversary (1607), Creator (1703)

Browse to Computer Configuration> Administrative Templates> Windows Components> Windows Updates> Defer Windows Updates.
Double click on the Select when Feature Updates are received.
Select Enabled.
Switch Current Branch to Current Branch for Business
Set the delay days to 180. (Since Creator Update 1703, you can now defer up to 365 days)
Click on OK to close this window.

Double click on the Select when Quality Updates are received.
Select Enabled.
Set the delay days to 30.
Click on OK to close this window.

You can now close the Group Policy Editor window.
The computer must be restarted for such changes to apply.

On Windows Fall Creator (1709) Spring Creator (1803) October 2018 (1809) May 2019 (1903) November 2019 (1909) May 2020 (2004) Fall 2020 (20H2) May 2021 (21H1) November 2021 (21H2)

Browse to Computer Configuration> Administrative Templates> Windows Components> Windows Updates> Windows Update for Business
Double click on the Select when Preview builds and Feature Updates are received.
Select Enabled.
Switch to Semi-Annual Channel
Set the delay days to to 365 days.
Click on OK to close this window.

Double click on the Select when Quality Updates are received.
Select Enabled.
Set the delay days to 30.
Click on OK to close this window.

You can now close the Group Policy Editor window.
The computer must be restarted for such changes to apply.

Prevent Windows 10 update to new Major version

Since Windows 1803, it is possible to prevent Windows 10 to upgrade to a new major version.
Such update will not be automatically downloaded and installed on your computer, but it is still possible to update manually, with Microsoft Update Assistant.
(MassCore users should first make sure that the MassCore engine is compatible before upgrading to a new Windows version - see this page).

Please note that Merging can't guarantee that this setting will continue to work with new Windows 10 versions.
According to Microsoft "it will work until the policy is changed to a newer Windows 10 feature update.”

Download and extract the following zip file
Double click on the WindowsTargetReleaseVersionInfo.reg file to add it to your Windows registry
Open Windows Registry Editor (Regedit.exe) and browse to HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows\WindowsUpdate
Double click on WindowsTargetReleaseVersionInfo and enter your current Windows version.
You can easily get your current Windows version by typing winver in Windows search field or Run command.

Note for MassCore users above 22H1

MassCore users with the latest Windows 10 versions will still have a warning message upon opening Pyramix.
This is due to a no longer present registry key checked at Pyramix's launch. To remedy this :

Download the "Branch Readiness Level" key : https://download.merging.com/beta/SupportTools/MTBranchReadiness.zip
Extract the zip
From Windows search, open "regedit" as administrator
Click "File>Import>Select the unzipped key"
Hit ok

Feature vs Quality updates ?

Quality Update provides fixes but no new functionality while the Feature Update provides new features.