Use RX Connect with Pyramix FX Rendering.

Edit audio from Pyramix FX Rendering tab in RX Audio Editor

1. In the FX Rendering tab, right click in the Effects Graph zone.
   If the FX Rendering tab is not displayed, it can be accessed through View > Editor Tabs > FX Rendering.
2. Select VST3 > Izotope, Inc.  > RX 7 Connect
   
3. Configure the Audio Input.
   Default is Stereo.  Click on the drop down menu to select another input layout, otherwise go to step 5.
   
   
   
4. Right click on the RX Connect node and select Configure Audio I/O
   Default is Stereo.  Click on the Channel Layout drop down menu to select another layout.
   
   
   
5. Right click on the RX Connect node and this time select Auto-connect pins
   You may also manually connect the pins between RX Connect and the inputs / outputs
   
6. Double click on the RX Connect node to open its UI and set it to Repair mode.
   
7. Select a clip in the Pyramix timeline. Remember that RX can handle up to 8 tracks *
8. Configure the Processing according to your needs; Process clips individually / Process the whole region (see Pyramix user manual for further details)
9. Press on Render
   The audio is now transferred in Izotope RX application
10. Edit your file in RX.
11. When finished, click on Send Back in RX.
    
12. Back in Pyramix, click on Render to get the processed file in Pyramix timeline.
    
    

* The RX 7 Audio Editor standalone application provides multichannel support for channel counts as high as 7.1. RX Connect and RX Monitor support multichannel so far as to transfer the multichannel audio from your DAW to the standalone application.
For more Channels support it is possible to export your multichannel audio from your Pyramix DAW and import it into RX 7 Audio Editor manually.

Monitor RX Audio Editor in Pyramix

1. With RX Monitor :
   In RX Audio Editor, go in Edit > Preferences menu.
   In the audio tab, set the Driver type to RX Monitor
   In Pyramix, add the RX Monitor VST plugin in your Mixer, on a strip or bus corresponding to the required channel layout.
   
   
2. With MT ASIO Bridge :
   Go in VS3 Control Panel and activate the Audio Bridge in MT ASIO Bridge Host.
   In RX Audio Editor, go in Edit > Preferences menu.
   In the audio tab, set the Driver type to ASIO, set the device to MT ASIO Bridge.
   Untick the Release when not in use option (may generate noise when not in use).
   
   Map the required inputs in your mixer strips, and set your strips in Input monitoring mode.
   In this configuration, Pyramix must be started before RX (as it hosts the ASIO bridging device).